Prenatal detection (PND) of congenital heart disease (CHD) varies across the nation and is dependent on many factors, including by diagnosis. Nationwide prenatal detection rates average about 50%. Quartermain et al. study (2006-2012) estimated AZ prenatal detection to be 40%. In 2013 prenatal screening ultrasound guidelines were changed to include outflow tract sweeps. Prenatal diagnosis allows for appropriate delivery planning and direction for postnatal management We performed a retrospective study including 1075 patients in Arizona from 2012-2018. Data was collected by chart review and patients were identified from the Society of Thoracic Surgeons Database. We included infants with hemodynamically significant CHD requiring cardiac surgery prior to 1 year. Primary aims were to estimate prenatal detection rate of CHD in Arizona based on a single center’s experience and to describe various factors that may influence detection rates. Secondary Aims were to assess if there is an association between prenatal detection and outcomes as well as to investigate descriptors of primary and secondary aims (such as type of cardiac lesion, presence of chromosomal abnormalities, time until surgery). We found that overall prenatal detection rate of 51%. There was a significant Improvement in detection rate every year, with the highest rate of 61% in 2018. High risk pregnancies and those with chromosomal abnormalities had higher detection rates. Single ventricle lesions are detected at a higher rate compared to other congenital heart defects (79.9%). Patients with prenatally detected HLHS had 3 days shorter time to surgery (7.5 vs. 10.2 days P 0.04). Additionally, lesions requiring 4 chamber view for detection have significantly higher prenatal detection. In conclusion, a higher prenatal detection rate was seen compared to what had previously been reported in Arizona. Yearly improvement in PND may be an effect of 2013 screening guidelines. Improvement in diagnosis of CHD lesions seen on outflow sweeps. Future interventions to improve prenatal detection should include continued education on outflow tract and three vessel views on prenatal screening.